Pancreatitis In Pregnancy-A Scenario In A Tertiary Care Centre

Objectives: To study the etiology and outcome of pregnancy with pancreatitis. Methods: The study was conducted in the department of Gynecology & Obstetrics along with School of Digestive & Liver Diseases (SDLD), IPGME & R, Kolkata between March 2006 to February 2009. We have analyzed 29 cases of acute pancreatitis in pregnancy over a period of 3 years. Maternal age, gravida/ parity, gestational age at presentation were noted, diagnostic tests ( serum amylase, lipase, LFT, triglycerides, calcium, urinary creatinine / amylase ratio, USG / CT scan ) were performed almost in all cases and ERCP in indicated cases. They were categorized as “ gallstone pancreatitis” & “ non-gallstone pancreatitis”. Results: The majority (69%) of cases of acute pancreatitis were caused by gallstones. Gallstone pancreatitis occured in relatively elder age (28.2 years) as compared to nongallstone pancreatitis (24.4 years). All the patients in non-gallstone pancreatitis and 62.10% patients in gallstone group were treated conservatively. There were poor pregnancy outcome like abortion, intrauterine fetal death, preterm delivery due to acute pancreatitis. Study revealed better pregnancy outcome in respect to term delivery in gallstone group (44.85%) in comparison to non-gallstone group (6.9%). We found one maternal death in non-gall stone group. Conclusion: This study adds substantially to our understanding of pancreatitis in pregnancy.